CRIOAc Lyon has published numerous BJI case reports in international medical journals. Lessons are learned with the treatment of every single patient. This knowledge gained by experience is valuable in the development of management algorithms and in the evaluation of medical and surgical strategies.
Case report: Continuous infusions of ceftazidime-avibactam and aztreonam in combination through elastomeric infusors for 12 weeks for the treatment of bone and joint infections due to metallo-β-lactamase producing Enterobacterales
Front Med (Lausanne). 2023; 10: 1224922.
Among carbapenem-resistant Enterobacterales, metallo-beta-lactamase producing strains represent a growing therapeutic challenge. While the association of aztreonam and ceftazidime-avibactam has been investigated in recent years for the treatment of infections involving these strains, little to no clinical data support the use of this association for the treatment of bone and joint infections. We report two cases of complex bone and joint