2025
Publications
- Peripheral neuropathy during long-term suppressive therapy with tedizolid: a case series
- Management of Gram-positive multiresistant bacteria prosthetic joint infection: a narrative review on current and innovative strategies
2024
Publications
Posters
- CIERNY AND MADER STAGE III ADULT LONG BONE CHRONIC OSTEOMYELITIS: RETROSPECTIVE STUDY AT THE LYON REFERENCE CENTRE FOR COMPLEX OSTEOARTICULAR INFECTIONS (CRIOAC)
- TWO NEW LOCAL POTENTIAL WEAPONS AS ADJUVANT DURING DAIR STRATEGY IN CHRONIC PERIPROSTHETIC JOINT INFECTIONS (PJI): A SINGLE CENTER RETROSPECTIVE STUDY
- Utilisation du STIMULAN® et du BACTISURE® dans les infections chroniques d’implants articulaires : une série rétrospective monocentrique
2023
Communications orales
- Monitoring of adverse events: Do we get the overall picture?
- Nouveaux concepts dans les infections sur matériel
Publications
Formation continue et webinaires
Posters
- Diagnostic, management and outcome of bone flap osteomyelitis following craniectomy: a cohort study
- Validation of a rabbit model of in vivo biofilm formation on beads for ex vivo evaluation of the antibiofilm activity of antistaphylococcal drugs
- Risk factors, management and outcome of early (<6 months) open fracture-related infections (FRI)
2022
Publications
- Staphylococcus lugdunensis prosthetic joint infection: A multicentric cohort study
- Necrotizing external otitis: analysis of relapse risk factors in 66 patients managed during a 12 year period
- Osteocutaneous-flap-related osteomyelitis following mandibular reconstruction: a cohort study of an emerging and complex bone infection
- Necrotizing external otitis: analysis of relapse risk factors in 66 patients managed during a 12 year period
Diplôme Inter-Universitaire
- Physiopathologie des IOA
- Diagnostic microbiologique des IOA
- Les modèles animaux et les IOA : apport de la littérature et expérience personnelle
- Activité intracellulaire et antibiofilm des antibiotiques
- Place de la rifampicine dans les IOA
- Allergies, intolérances aux antibiotiques
- IOA complexes au cours des infections de la tête et du cou
2021
Communications orales
DES et DESC de Maladies Infectieuses
Posters
- CEFTAROLINE AND CEFTOBIPROLE: REAL LIFE OFF LABEL USE IN PATIENTS WITH BJI OF THESE TWO BETALACTAMS ACTIVE AGAINST METHICILLIN-RESISTANT STAPHYLOCOCCI
- Coût des antibiothérapies hors AMM dans les infections ostéo-articulaires : Etude prospective observationnelle sur 6 ans dans un Centre de Référence pour la prise en charge des IOA complexes (CRIOAc)
- Conception et construction d’un bâtiment dédié aux maladies infectieuses et tropicales : huit années de travail concerté pour obtenir une structure innovante et modulable en fonction du risque épidémique
- Safety of tedizolid as suppressive antimicrobial therapy for patients with complex implant-associated bone and joint infection due to multidrug-resistant Gram-positive pathogens: results from the TediSAT cohort study
Publications
- Cost of off-label antibiotic therapy for bone and joint infections: a 6-year prospective monocentric observational cohort study in a referral centre for management of complex osteo-articular infections
- Safety of Tedizolid as Suppressive Antimicrobial Therapy for Patients With Complex Implant-Associated Bone and Joint Infection due to Multidrug-Resistant Gram-Positive Pathogens: Results From the TediSAT Cohort Study
- Evaluation of intraosteoblastic activity of dalbavancin against Staphylococcus aureus in an ex vivo model of bone cell infection
- Lysosomal alkalization to potentiate eradication of intra-osteoblastic Staphylococcus aureus in the bone and joint infection setting.
- Pharmacokinetic/Pharmacodynamic Dosage Individualization of Suppressive Beta-Lactam Therapy Administered by Subcutaneous Route in Patients With Prosthetic Joint Infection
2020
Publications
- Bone and Joint Infection Involving Corynebacterium spp.: From Clinical Features to Pathophysiological Pathways
- Pseudomonas aeruginosa Implant-Associated Bone and Joint Infections: Experience in a Regional Reference Center in France
- Plasma Cell Infiltration on Histopathological Samples of Chronic Bone and Joint Infections due to Cutibacterium acnes: A series of 21 Cases
- Tolerance and Microbiological Efficacy of Cefepime or piperacillin/tazobactam in Combination With Vancomycin as Empirical Antimicrobial Therapy of Prosthetic Joint Infection: A Propensity-Matched Cohort Study
- Duration of rifampin therapy is a key determinant of improved outcomes in early-onset acute prosthetic joint infection due to Staphylococcus treated with a debridement, antibiotics and implant retention (DAIR): a retrospective multicenter study in France
- Antibiofilm and intraosteoblastic activities of rifamycins against Staphylococcus aureus: promising in vitro profile of rifabutin
Diplôme Inter-Universitaire
Formation continue et webinaires
Communications orales
- Osteomyelitis following mandibular reconstruction with free fibula flap : a cohort study of an emerging and complex bone and joint infection
- Physiopathologie des infections ostéo-articulaires : Entre virulence et persistence
DES et DESC de Maladies Infectieuses
- Physiopathologie des IOA : Facteurs de virulence et de persistance bactérienne
- Principe du traitement médical : Infection aigüe sur prothèse
2019
Posters
- Tolerance and microbiological efficacy cefepim or piperacillin/tazobactam in combination with vancomycin as empirical antimicrobial therapy of PJI
- Denosumab related osteonecrosis of the jaw: an emergent and potentially complex bone and joint infection
- Infections ostéo-articulaire à S. aureus : activité intra-ostéoblastique et anti-biofilm des rifamycines
- L’alcalinisation phagolysosomale dans le traitement des infections ostéo-articulairesà Staphylococcus aureus
- Comparaison de deux modèles pharmacocinétiques pour le suivi thérapeutique de la daptomycine
- Immunothérapie préventive par MEDI6389, combinaison d’anticorps monoclonaux antialpha- toxine, leucocidine de Panton-Valentin et ED, gamma-hémolysine et clumping facteur A dans un modèle lapin d’infection de prothèse articulaire à SARM USA300
- Implementation and validation of a pharmacokinetic model for Bayesian therapeutic drug monitoring of daptomycin in patients with bone and joint infection
- Pharmacocinétique de la daptomycine dans les infections ostéo-articulaires : intérêt du suivi thérapeutique pharmacologique et de l’individualisation posologique
- Pseudomonas aeruginosa implant-associated Bone and Joint Infections : Experience in a Regional Reference Center in France
- Denosumab related osteonecrosis of the jaw: an emergent and potentially complex bone and joint infection
Publications
- Subcutaneous suppressive antibiotic therapy for bone and joint infections: safety and outcome in a cohort of 10 patients
- Subcutaneous teicoplanin in staphylococcal bone and joint infections
- Pubic osteomyelitis: Epidemiology and factors associated with treatment failure
- Interaction Between Staphylococcal Biofilm and Bone: How Does the Presence of Biofilm Promote Prosthesis Loosening?
- Evaluation of the ability of linezolid and tedizolid to eradicate intraosteoblastic and biofilm-embedded Staphylococcus aureus in the bone and joint infection setting
- Microbiologic epidemiology depending on time to occurrence of prosthetic joint infection: a prospective cohort study
Communications orales
2018
Diplôme Inter-Universitaire
- Les modèles animaux et les IOA : Apport de la littérature et expérience personnelle
- Activité intracellulaire et antibiofilm des antibiotiques
- Place de la rifampicine dans les IOA
- Allergies, intolérances aux antibiotiques
Posters
- Activité de nouvelles molécules anti-staphylococciques sur la persistance intra-ostéoblastique
- Infection de prothèse et changement en 1 temps : prétraitement par antibiothérapie ciblée chez des patients à risque
- Capacité du linézolide et du tédizolide à éradiquer Staphylococcus aureus en intracellulaire et sous forme de biofilm au cours du traitement des infections ostéo-articulaires
- Evaluation de l’utilisation de la céfoxitine en association en administration parentérale continue dans le traitement des infections ostéo-articulaires
- Infections chroniques sur prothèses articulaires (IPA) à Cutibacterium acnes diagnostiquées par PCR spécifique : une étude descriptive de 6 patients
- Infections ostéo-articulaires : activité intra-ostéoblastique des rifamycines et oxazolidinones
Cas cliniques
- Pott’s disease associated with large and multiple abscesses in a 30-year-old migrant from Chad
- Correction of Linezolid-Induced Myelotoxicity After Switch to Tedizolid in a Patient Requiring Suppressive Antimicrobial Therapy for Multidrug-Resistant Staphylococcus epidermidis Prosthetic-Joint Infection
Publications
- Association between biofilm formation phenotype and clonal lineage in Staphylococcus aureus strains from bone and joint infections
- Prospective Cohort Study of the Tolerability of Prosthetic Joint Infection Empirical Antimicrobial Therapy
- Prolonged Cefoxitin Infusion Using Mobile Elastomeric Infusors In Outpatients With Bone And Joint Infection
- Outpatient parenteral antibiotic therapy: Evaluation of practices and limits of use in rural areas in France
- Population pharmacokinetics and probability of target attainment of ertapenem administered by subcutaneous or intravenous route in patients with bone and joint infection
- Pressure ulcer-related pelvic osteomyelitis: evaluation of a two-stage surgical strategy (debridement, negative pressure therapy and flap coverage) with prolonged antimicrobial therapy
Formation continue et webinaires
2017
Thèses
Posters
- Microbiological epidemiology in patients experiencing microbiological or clinical failure following reimplantation after a 2-stage exchange strategy for hip or knee prosthetic joint infection (PJI)
- Pressure ulcer-related pelvic osteomyelitis : Evaluation of a two-stage surgical strategy (debridement, negative pressure therapy and flap coverage) with prolonged antimicrobial therapy
- Microbiological epidemiology depending on time to occurrence of prosthetic joint infection (PJI) : impact on the empirical antimicrobial strategies
- Pubic osteomyelitis (PO) : Epidemiology and factors associated with management failure in two French Reference Centers
- Subcutaneous Suppressive Antibiotic Therapy for Bone and Joints Infections: Safety and Outcome in a Cohort of 10 Patients
Cas cliniques
Publications
2016
Posters
- Investigation of the ability to be internalized in osteoblasts as a pathophysiological mechanism involved in Staphylococcus non-aureus bone and joint infection
- Pharmacokinetics of Ertapenem Administered by Intravenous or Subcutaneous Route in Patients with Bone and Joint Infections: Population and Monte Carlo simulation study
DES et DESC de Maladies Infectieuses
Cas cliniques
- Mycobacterium bovis prosthetic joint infection
- Chronic tibial pandiaphysitis with Brodie abscess due to Salmonella saprophyticus in a 29-year-old healthy man
Publications
- Methicillin-susceptible strains responsible for postoperative orthopedic infection are not selected by the use of cefazolin in prophylaxis
- Adaptive processes of Staphylococcus aureus isolates during the progression from acute to chronic bone and joint infections in patients
- Diffuse Escherichia coli gaseous abscesses
- Pristinamycin in the treatment of MSSA bone and joint infection
- Teicoplanin-based antimicrobial therapy in Staphylococcus aureus bone and joint infection: tolerance, efficacy and experience with subcutaneous administration
- Daptomycin > 6 mg/kg/day as salvage therapy in patients with complex bone and joint infection: cohort study in a regional reference center
- Pharmacokinetic Variability of Daptomycin during Prolonged Therapy for Bone and Joint Infections
- Pathophysiological Mechanisms of Staphylococcus Non-aureus Bone and Joint Infection: Interspecies Homogeneity and Specific Behavior of S. pseudintermedius
2015
Posters
- Autologous Bone Flap infection Following Craniectiomy: Clinical Experience in a Referral Center
- Evidence of adaptative processes of Staphylococcus aureus isolates in the course of chronic bone and joint infections in patients
- Management of P. acnes bone and joint infection in a regional reference centre in France
Cas cliniques
- A 22-year-old woman with right lumpy jaw syndrome and fistula
- Daptomycin-induced eosinophilic pneumonia
- Metallosis-associated prosthetic joint infection
Publications
- Antimicrobial activity against intraosteoblastic Staphylococcus aureus
- Delta-toxin production deficiency in Staphylococcus aureus: a diagnostic marker of bone and joint infection chronicity linked with osteoblast invasion and biofilm formation
- Methicillin-susceptible strains responsible for postoperative orthopedic infection are not selected by the use of cefazolin in prophylaxis
Thèses
2014
Communications orales
Publications
- Rapid detection of Staphylococcus aureus and methicillin resistance in bone and joint infection samples: evaluation of the GeneXpert MRSA/SA SSTI assay
- Determinants of methicillin-susceptible Staphylococcus aureus native bone and joint infection treatment failure: a retrospective cohort study.
- Antimicrobial-related Severe Adverse Events During Treatment of Bone and Joint Infection Due to Methicillin-Susceptible Staphylococcus Aureus
- Methicillin-susceptible Staphylococcus Aureus Clonal Complex 398: High Prevalence and Geographical Heterogeneity in Bone and Joint Infection and Nasal Carriage
- Activation of NK cells in patients with chronic bone and joint infection due to staphylococci expressing or Not the small colony variant phenotype.
- Actinomycosis : etiology, clinical features, diagnosis, treatment and management
- Risk factors, diagnosis and management of bone flap osteomyelitis following craniectomy