Cefoxitin: Interesting Perspectives on a Neglected Intravenous Beta-lactam
Cefoxitin is a beta-lactam antibiotic belonging to the cephamycins class, up to now only used in clinical practice for prophylaxis during surgery. Recently, its use has increased due to the spread of infections caused by extended-spectrum beta-lactamase-producing bacteria, particularly urinary tract infections. It has a broad antimicrobial spectrum and is also effective in polymicrobial bone and joint infections or skin and soft tissue infections. Stability data allows its use as a continuous infusion in intensive care units or with elastomeric diffuser for outpatients. Cefoxitin is well tolerated. The aim of this article was to highlight the interesting aspects of this old and inexpensive intravenous beta-lactam.